Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
Pevonedistat - an overview | ScienceDirect Topics
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Figure 5 | Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication | Bentham Science
A model for the role of MLN4924 in mtOr signaling inactivation.... | Download Scientific Diagram
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram
Neddylation regulation of mitochondrial structure and functions | Cell & Bioscience | Full Text
Cancers | Free Full-Text | Drug Development Targeting the Ubiquitin–Proteasome System (UPS) for the Treatment of Human Cancers
Cancers | Free Full-Text | Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer Research | Full Text
The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation - ScienceDirect
Pevonedistat - an overview | ScienceDirect Topics
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy | Antioxidants & Redox Signaling
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer | Cell Death Discovery
